Saturday, June 4, 2011

Opioid analgesics : types

Internationally accepted classification of analgesics does not exist.Some textbooks classify them for effectiveness in relieving either weak or strong pain. Others divide them according to the place at which they work - or at a pain center or on the brain. Painkillers that act at the source of pain, block the generation of an prostaglandins, which in turn prevents the stimulation of nerve endings, so that the pain signal does not reach the brain, the same as vozdeytvuyut on the brain, blocking the transmission of pain signals between brain cells and thus prevent a feeling pain .Another approach is the division of narcotic or opioid analgesics (natural or synthesized, which action similar to the action of morphine) and non-narcotic, or neopiodnye, analgesics (eg aspirin). Narcotic analgesics may cause drug dependence. They are often used effectively to relieve severe pain, especially in the internal organs, but also in other parts of the body. Non-opioid analgesics used for relief of skin, muscle, dental pain, pain in joints and bones . Another classification divides the pain on those that just relieve the pain and fever (antipyretics), and those that eliminate pain, fever and help reduce inflammation . The latter are usually called non-steroidal anti-inflammatory drugs (NSAIDs), or aspirinopodobnymi drugs (NSAIDs as the first representative was aspirin) .

Narcotic analgesics in most countries, usually subject to strict scrutiny, and are reserved for use in cases of severe pain, such as after surgery or for cancer patients in terminal stage. In respect of non-narcotic analgesics acting fewer restrictions. In most countries, the market there are dozens of such drugs.

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