Monday, June 6, 2011

Opioid Analgesics : prolonged use

Widely believed that prolonged use of opioid analgesics for relief of chronic pain often leads to abuse of drugs and drug addiction. Society and the media focus attention on the problem of medical drug due to the fact that doctors are increasingly prescribing narcotic drugs. His view on this issue poses the chief editor of Pain Treatment Topics Stewart B. Master Medicine Levitt (Stewart B. Leavitt). After analyzing a set of clinical studies and scientific articles on the subject specialist in pain argues that the danger of drug abuse patients is not as great as it seems at first glance. In the review he cites some of these studies.

Opiates (opium alkaloids), such as morphine, and their synthetic counterparts. Today considered to be the only drug which removes a very strong or chronic pain. Different opioid analgesics act in the body through different types of opioid receptors, in most cases through the m-receptors.
DA Fishbayn (DA Fishbain) from the University of Miami (Miller School of Medicine at the University of Miami) in Florida in 2008 summarized 24 studies. Of 2507 patients who were receiving treatment of opioid analgesics for relief of chronic pain noncancerous origin, symptoms of abuse of drugs and drug abuse occurred in 3.27%. It was found that the primary addiction was formed only 0.19% of patients and others have already had in the past experience of drug use.
Srinivaza Raja (Srinivasa Raja) of Johns Hopkins University (Johns Hopkins University School of Medicine) in May 2008 at the annual meeting of the American Society for the Study of the effects of pain (American Pain Society) said that the overall proportion of patients who manifest dependence on opiates, generally less than 3%.
M. Noble (M. Noble) and co-workers from the Research Institute of Emergency (ECRI) reviewed 115 clinical trials prolonged use of opioid analgesics and chose the 17 most deserving of trust. Patients with chronic pain noncancerous origin, from mild to severe, taking opioids for at least six months. Abused drugs, only three of 685 (0.4%) patients, and symptoms of drug dependence have only one of 2,042 (0.05%) patients. True, this is not specified whether these historically low rates to all patients or only to those who have no experience of drug use.

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