Monday, June 6, 2011

Opioid analgesics optimization methods of drug administration

The most effective efforts to improve the quality of postoperative opioid analgesics usage, based on the optimization methods of drug administration

The most modern method is controlled by the patient's intravenous analgesia (KPVA), most focused on the individual needs of the patient's anesthesia. If necessary, by clicking on the remote device, the patient himself, introduces an additional bolus of analgesic (typically 2 mg of morphine), which gives it a sense of independence and confidence, and facilitates the work of nurses. This methodology is characterized by high efficiency and relative safety. According to this previously mentioned large British study, the frequency of reducing the saturation of capillary blood oxygen during KPVA IRS was 11.5%, while their intramuscular injection - 37% (Dolin S., Cashman J., 2002). Prospects for patient-controlled opioid analgesics usage in our country are limited accounting problems and cheating of opioid analgesics.
    Traditionally, systemic administration of opioids was considered as a basis for postoperative analgesia. At the same time, the effectiveness of pain management in the traditional appointment of opioids as a monotherapy does not exceed 25-30%. The problem is that an effective analgesic dose is often close to that cause depression of respiration.
   The appointment of postoperative opioid analgesics is associated with an increase in the number of postoperative complications and increases the cost of the patient's stay in the clinic.

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